This is the 73rd episode in my drug pronunciation series. In this episode, I divide hydrochlorothiazide into syllables, tell you which syllables to emphasize, list my sources, and introduce some bonus topics: one pronunciation variation and two abbreviations.
Why did I pick hydrochlorothiazide for this episode?
- It is frequently prescribed.
- It’s a long, intimidating drug name.
- It is found in combination with other blood pressure medications.
- It’s a drug name in my pronunciation course, which ends in December 2026.
There are still more than 50 drug names in the course that have not been part of the pronunciation series. It is my goal to include all 50+ in the drug pronunciation series eventually.
❌ We don’t cover pharmacology in this series. Just pronunciations.
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Hydrochlorothiazide = HYE-droe-KLOR-oh-THYE-a-zide (7 syllables)
- HYE, like high blood pressure
- droe, like a drone
- KLOR, like chloride
- oh, like the letter “O” in the alphabet
- THYE, like the body part, thigh
- a, which is a short “A” sound, like the “a” in adoption (uh)
- zide, which rhymes with tide, as in the ocean tide
- Emphasize HYE, KLOR, and THYE. THYE gets the most emphasis.
- Written pronunciation source: MedlinePlus.gov
- Spoken pronunciation example: Tony PharmD HCTZ pronunciation (YouTube)
Pronunciation Variation
As an Ohio Pharmacist, I tend to say HYE-droe-KLOR-uh-THYE-a-zide instead of HYE-droe-KLOR-oh-THYE-a-zide. They sound VERY similar. The difference is “uh” vs “oh.” Either spoken pronunciation will pass as correct. They’re both “in the ballpark.”
Two abbreviations
- HCTZ
- HCT
If you know someone who would like to learn how to say hydrochlorothiazide, please share this episode with them. Subscribe to or follow The Pharmacist’s Voice ® Podcast on your favorite podcast player and YouTube, so you never miss an episode. This podcast is on all major podcast players and YouTube.
Host Background: Kim Newlove has been an Ohio pharmacist since 2001 (BS Pharm, Chem Minor). Her experience includes hospital, retail, compounding, and behavioral health. She is also an author, voice actor (medical narrator and audiobook narrator), podcast host, and consultant (podcasting and audiobooks).
Other episodes in this series
The Pharmacist’s Voice Podcast Episode 370, Pronunciation Series Episode 72 oseltamivir (Tamiflu)
The Pharmacist’s Voice Podcast Episode 364, Pronunciation Series Episode 71 (Dupixent)
The Pharmacist’s Voice Podcast Episode 362, Pronunciation Series Episode 70 (Corlanor)
The Pharmacist’s Voice Podcast Episode 360, Pronunciation Series Episode 69 (Kisunla)
The Pharmacist’s Voice Podcast Episode 358, Pronunciation Series Episode 68 (Journavx)
The Pharmacist’s Voice Podcast Episode 356, Pronunciation Series Episode 67 (Zanaflex)
The Pharmacist’s Voice Podcast Episode 352, Pronunciation Series Episode 66 (Yescarta)
The Pharmacist’s Voice Podcast Episode 350, Pronunciation Series Episode 65 (Xarelto)
The Pharmacist’s Voice Podcast Episode 349, Pronunciation Series Episode 64 (acetaminophen)
The Pharmacist’s Voice Podcast Episode 348, Pronunciation Series Episode 63 (Welchol/colesevelam)
The Pharmacist’s Voice Podcast Episode 346, Pronunciation Series Episode 62 (valacyclovir)
The Pharmacist’s Voice Podcast Episode 343, Pronunciation Series Episode 61 (ubrogepant)
The Pharmacist’s Voice Podcast Episode 341, Pronunciation Series Episode 60 (topiramate)
The Pharmacist’s Voice Podcast Episode 339, Pronunciation Series Episode 59 (Suboxone)
The Pharmacist’s Voice Podcast Episode 337, Pronunciation Series Episode 58 (rosuvastatin)
The Pharmacist’s Voice Podcast Episode 335, Pronunciation Series Episode 57 (QVAR)
The Pharmacist’s Voice Podcast Episode 333, Pronunciation Series Episode 56 (pantoprazole)
The Pharmacist’s Voice Podcast Episode 330, Pronunciation Series Episode 55 (oxcarbazepine)
The Pharmacist’s Voice Podcast Episode 328, Pronunciation Series Episode 54 (nalmefene)
The Pharmacist’s Voice Podcast Episode 326, Pronunciation Series Episode 53 (Myrbetriq)
The Pharmacist’s Voice Podcast Episode 324, Pronunciation Series Episode 52 (liraglutide)
The Pharmacist’s Voice Podcast Episode 322, Pronunciation Series Episode 51 (ketamine)
The Pharmacist’s Voice Podcast Episode 320, Pronunciation Series Episode 50 (Jantoven)
The Pharmacist’s Voice Podcast Episode 318, Pronunciation Series Episode 49 (ipratropium)
The Pharmacist’s Voice Podcast Episode 316, Pronunciation Series Episode 48 (hyoscyamine)
The Pharmacist’s Voice Podcast Episode 313, Pronunciation Series Episode 47 (guaifenesin)
The Pharmacist’s Voice Podcast Episode 311, Pronunciation Series Episode 46 (fluticasone)
The Pharmacist’s Voice Podcast Episode 309, Pronunciation Series Episode 45 (empagliflozin)
The Pharmacist’s Voice Podcast Episode 307, Pronunciation Series Episode 44 (dapagliflozin)
The Pharmacist’s Voice Podcast Episode 304, Pronunciation Series Episode 43 (cetirizine)
The Pharmacist’s Voice Podcast Episode 302, Pronunciation Series Episode 42 (buspirone)
The Pharmacist’s Voice Podcast Episode 301, Pronunciation Series Episode 41 (azithromycin)
The Pharmacist’s Voice Podcast Episode 298, Pronunciation Series Episode 40 (umeclidinium)
The Pharmacist’s Voice Podcast Episode 296, Pronunciation Series Episode 39 (Januvia)
The Pharmacist’s Voice Podcast Episode 294, Pronunciation Series Episode 38 (Yasmin)
The Pharmacist’s Voice Podcast Episode 292, Pronunciation Series Episode 37 (Xanax, alprazolam)
The Pharmacist’s Voice Podcast Episode 290, Pronunciation Series Episode 36 (quetiapine)
The Pharmacist’s Voice Podcast Episode 287, pronunciation series ep 35 (bupropion)
The Pharmacist’s Voice Podcast Episode 285, pronunciation series ep 34 (fentanyl)
The Pharmacist’s Voice Podcast Ep 281, Pronunciation Series Ep 33 levothyroxine (Synthroid)
The Pharmacist’s Voice ® Podcast Ep 278, Pronunciation Series Ep 32 ondansetron (Zofran)
The Pharmacist’s Voice ® Podcast Episode 276, pronunciation series episode 31 (tocilizumab-aazg)
The Pharmacist’s Voice ® Podcast Episode 272, pronunciation series episode 29 (losartan)
The Pharmacist’s Voice Podcast Episode 269, pronunciation series episode 28 (tirzepatide)
The Pharmacist’s Voice Podcast Episode 267, pronunciation series episode 27 (atorvastatin)
The Pharmacist’s Voice Podcast Episode 265, pronunciation series episode 26 (omeprazole)
The Pharmacist’s Voice Podcast Episode 263, pronunciation series episode 25 (PDE-5 inhibitors)
The Pharmacist’s Voice Podcast Episode 259, pronunciation series episode 24 (ketorolac)
The Pharmacist’s Voice ® Podcast episode 254, pronunciation series episode 23 (Paxlovid)
The Pharmacist’s Voice ® Podcast episode 250, pronunciation series episode 22 (metformin/Glucophage)
The Pharmacist’s Voice Podcast ® episode 245, pronunciation series episode 21 (naltrexone/Vivitrol)
The Pharmacist’s Voice ® Podcast episode 240, pronunciation series episode 20 (levalbuterol)
The Pharmacist’s Voice ® Podcast episode 236, pronunciation series episode 19 (phentermine)
The Pharmacist’s Voice ® Podcast episode 228, pronunciation series episode 18 (ezetimibe)
The Pharmacist’s Voice ® Podcast episode 219, pronunciation series episode 17 (semaglutide)
The Pharmacist’s Voice ® Podcast episode 215, pronunciation series episode 16 (mifepristone and misoprostol)
The Pharmacist’s Voice ® Podcast episode 211, pronunciation series episode 15 (Humira®)
The Pharmacist’s Voice ® Podcast episode 202, pronunciation series episode 14 (SMZ-TMP)
The Pharmacist’s Voice ® Podcast episode 198, pronunciation series episode 13 (carisoprodol)
The Pharmacist’s Voice ® Podcast episode 194, pronunciation series episode 12 (tianeptine)
The Pharmacist’s Voice ® Podcast episode 188, pronunciation series episode 11 (insulin icodec)
The Pharmacist’s Voice ® Podcast episode 184, pronunciation series episode 10 (phenytoin and isotretinoin)
The Pharmacist’s Voice ® Podcast episode 180, pronunciation series episode 9 Apretude® (cabotegravir)
The Pharmacist’s Voice ® Podcast episode 177, pronunciation series episode 8 (metoprolol)
The Pharmacist’s Voice ® Podcast episode 164, pronunciation series episode 7 (levetiracetam)
The Pharmacist’s Voice ® Podcast episode 159, pronunciation series episode 6 (talimogene laherparepvec or T-VEC)
The Pharmacist’s Voice ® Podcast episode 155, pronunciation series episode 5 Trulicity® (dulaglutide)
The Pharmacist’s Voice ® Podcast episode 148, pronunciation series episode 4 Besponsa® (inotuzumab ozogamicin)
The Pharmacist’s Voice ® Podcast episode 142, pronunciation series episode 3 Zolmitriptan and Zokinvy
The Pharmacist’s Voice ® Podcast episode 138, pronunciation series episode 2 Molnupiravir and Taltz
The Pharmacist’s Voice ® Podcast episode 134, pronunciation series episode 1 Eszopiclone and Qulipta
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Thank you for listening to episode 374 of The Pharmacist’s Voice ® Podcast. If you know someone who would like this episode, please share it with them!
List of drugs yet to be covered
- Abciximab
- Acetazolamide
- Adapalene
- Amoxicillin
- Aripiprazole
- Carbamazepine
- Celecoxib
- Clonazepam
- Colchicine
- Cyanocobalamin
- Dextroamphetamine
- Diazepam
- Diltiazem
- Divalproex
- Docusate sodium
- Duloxetine
- Estradiol
- Fluoxetine
- Gabapentin
- Gemfibrozil
- Hydralazine
- Hydrochlorothiazide
- Hydroxychloroquine sulfate
- Hydroxyzine HCl (Atarax)
- Hydroxyzine pamoate (Vistaril)
- Ibuprofen
- Ketotifen
- Levocetirizine
- Linagliptin
- Metoclopramide
- Methylprednisolone
- Morphine
- Mupirocin
- Nortriptyline
- Oxybutynin
- Oxycodone
- Paroxetine
- Phenazopyridine
- Phytonadione
- Polyethylene glycol 3350
- Pramipexole
- Pregabalin
- Rabeprazole
- Risperidone
- Ropinirole
- Salmeterol/fluticasone in combination
- Saxagliptin
- Sertraline
- Sevelamer
- Sucralfate
- Tramadol
- Trazodone